The PI3K/Akt pathway in tumors of endocrine tissues

The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is a key driver in carcinogenesis. Defects in this pathway in human cancer syndromes such as Cowden’s disease and Multiple Endocrine Neoplasia result in tumors of endocrine tissues, highlighting its importance in these cancer types. This review ex...

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Bibliographic Details
Main Authors: Helen Louise Robbins, Angela eHague
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00188/full