GLAST deficiency in mice exacerbates gap detection deficits in a model of salicylate-induced tinnitus

GLAST deficiency in mice exacerbates gap detection deficits in a model of salicylate-induced tinnitus

Gap detection or gap pre-pulse inhibition of the acoustic startle (GPIAS) has been successfully used in rat and guinea pig models of tinnitus, yet this system has proven to have low efficacy in CBA mice, with low basal GPIAS and subtle tinnitus like effects. Here, we tested five mouse strains (CBA,...

Full description

Bibliographic Details
Main Authors: Hong Yu, Kim Vikhe Patil, Chul Han, Brian Fabella, Barbara Canlon, Shinichi Someya, Christopher R. Cederroth
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Hearing Loss
Tinnitus
Mouse
gap detection
Disease Models, Animal
startle response
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00158/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00158/full

Similar Items