Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine–Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors

A series of novel thienopyridines and pyridothienoquinolines (<b>3a,b&#8722;14</b>) was synthesized, starting with 2-thioxo-1,2-dihydropyridine-3-carbonitriles <b>1a</b> and <b>1b</b>. All compounds were evaluated for their in vitro antimicrobial activity agai...

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Bibliographic Details
Main Authors: Eman M. Mohi El-Deen, Eman A. Abd El-Meguid, Sherifa Hasabelnaby, Eman A. Karam, Eman S. Nossier
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/20/3650