Quercetin Decreases Claudin-2 Expression Mediated by Up-Regulation of microRNA miR-16 in Lung Adenocarcinoma A549 Cells

Quercetin Decreases Claudin-2 Expression Mediated by Up-Regulation of microRNA miR-16 in Lung Adenocarcinoma A549 Cells

Claudin-2 is highly expressed in human lung adenocarcinoma tissues and cells. Knockdown of claudin-2 decreases cell proliferation and migration. Claudin-2 may be a novel target for lung adenocarcinoma. However, there are no physiologically active substances of foods which decrease claudin-2 expressi...

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Bibliographic Details
Main Authors: Hiroyuki Sonoki, Tomonari Sato, Satoshi Endo, Toshiyuki Matsunaga, Masahiko Yamaguchi, Yasuhiro Yamazaki, Junko Sugatani, Akira Ikari
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Nutrients
Subjects:
lung adenocarcinoma
claudin-2
miR-16
quercetin
Online Access:http://www.mdpi.com/2072-6643/7/6/4578

Internet

http://www.mdpi.com/2072-6643/7/6/4578

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