Evolutionary epidemiology of drug-resistance in space.

How can we optimize the use of drugs against parasites to limit the evolution of drug resistance? This question has been addressed by many theoretical studies focusing either on the mixing of various treatments, or their temporal alternation. Here we consider a different treatment strategy where the...

Full description

Bibliographic Details
Main Authors: Florence Débarre, Thomas Lenormand, Sylvain Gandon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2658742?pdf=render