Single rapamycin administration induces prolonged downward shift in defended body weight in rats.

Single rapamycin administration induces prolonged downward shift in defended body weight in rats.

Manipulation of body weight set point may be an effective weight loss and maintenance strategy as the homeostatic mechanism governing energy balance remains intact even in obese conditions and counters the effort to lose weight. However, how the set point is determined is not well understood. We sho...

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Bibliographic Details
Main Authors: Mark Hebert, Maria Licursi, Brittany Jensen, Ashley Baker, Steve Milway, Charles Malsbury, Virginia L Grant, Robert Adamec, Michiru Hirasawa, Jacqueline Blundell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4008417?pdf=render

Internet

http://europepmc.org/articles/PMC4008417?pdf=render

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