Hemophagocytic lymphohistiocytosis in children: pathogenesis and treatment
Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder in children, which is characterized by fever and hepatosplenomegaly associated with pancytopenia, hypertriglyceridemia and hypofibrinogenemia. Increased levels of various cytokines and soluble IL-2 receptors are biological markers of HLH. H...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2016-05-01
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Series: | Frontiers in Pediatrics |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fped.2016.00047/full |