Second messenger signaling in Bacillus subtilis: accumulation of cyclic di-AMP inhibits biofilm formation

Second messenger signaling in Bacillus subtilis: accumulation of cyclic di-AMP inhibits biofilm formation

The Gram-positive model organism Bacillus subtilis produces the essential second messenger signaling nucleotide cyclic di-AMP. In B. subtilis and other bacteria, c-di-AMP has been implicated in diverse functions such as control of metabolism, cell division and cell wall synthesis, and potassium tran...

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Bibliographic Details
Main Authors: Jan eGundlach, Hermann eRath, Christina eHerzberg, Ulrike eMäder, Jörg eStülke
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Microbiology
Subjects:
Bacillus subtilis
phosphodiesterase
Biofilm formation
c-di-AMP
SINR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00804/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00804/full

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