Nonlinearity of a Voltage-Gated Potassium Channel Revealed by the Mechanical Susceptibility

The voltage-gated potassium channel from Aeropyrum pernix operates by coupling the voltage-driven motion of a charged group of amino acids to the opening and closing of the pore. In this experiment, we drive this charged group with an ac field and observe the effect on the gating. The measurements f...

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Bibliographic Details
Main Authors: Amila Ariyaratne, Giovanni Zocchi
Format: Article
Language:English
Published: American Physical Society 2013-02-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/PhysRevX.3.011010