Falcarindiol Enhances Cisplatin Chemosensitivity of Hepatocellular Carcinoma via Down-Regulating the STAT3-Modulated PTTG1 Pathway

Falcarindiol Enhances Cisplatin Chemosensitivity of Hepatocellular Carcinoma via Down-Regulating the STAT3-Modulated PTTG1 Pathway

Hepatocellular carcinoma (HCC) is the most frequent primary liver malignancy globally and the third leading cause of cancer-related death. Chemotherapy is one of the main methods in treating HCC, while recent studies have found that the resistance of HCC to chemotherapeutic drugs reduces the efficac...

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Bibliographic Details
Main Authors: Han Hong, Zhengkang Jin, Tao Qian, Xiaoyong Xu, Xiang Zhu, Qiang Fei, Jiamei Yang, Chengjun Sui, Minhui Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
falcarindiol
hepatocellular carcinoma
cisplatin chemosensitivity
stat3
PTTG1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.656697/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.656697/full

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