Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity through the Control of Oxidative Phosphorylation

Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity through the Control of Oxidative Phosphorylation

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies with an overall survival of 5% and is the second cause of death by cancer, mainly linked to its high metastatic aggressiveness. Accordingly, understanding the mechanisms sustaining the PDAC metastatic phenotype remains a pr...

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Bibliographic Details
Main Authors: Gilles Rademaker, Brunella Costanza, Sandy Anania, Ferman Agirman, Naïma Maloujahmoum, Emmanuel Di Valentin, Jean Jacques Goval, Akeila Bellahcène, Vincenzo Castronovo, Olivier Peulen
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
myoferlin
pancreas cancer
mitochondria
oxidative phosphorylation
metastasis
Online Access:https://www.mdpi.com/2072-6694/11/6/853

Internet

https://www.mdpi.com/2072-6694/11/6/853

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