Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study

Summary: Background: Drug resistance threatens global tuberculosis control. We aimed to examine mortality in patients with tuberculosis from high-burden countries, according to concordance or discordance of results from drug susceptibility testing done locally and whole-genome sequencing (WGS). Met...

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Main Authors: Kathrin Zürcher, MSc, Martina L Reichmuth, MSc, Marie Ballif, PhD, Chloé Loiseau, PhD, Sonia Borrell, PhD, Miriam Reinhard, Veronika Skrivankova, PhD, Rico Hömke, Peter Sander, MD, Anchalee Avihingsanon, MD, Alash'le G Abimiku, ProfPhD, Olivier Marcy, MD, Jimena Collantes, MSc, E Jane Carter, MD, Robert J Wilkinson, ProfPhD, Helen Cox, ProfPhD, Marcel Yotebieng, ProfMD, Robin Huebner, PhD, Lukas Fenner, ProfMD, Erik C Böttger, ProfMD, Sebastien Gagneux, ProfPhD, Matthias Egger, ProfMD
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:The Lancet Microbe
Online Access:http://www.sciencedirect.com/science/article/pii/S2666524721000446