Human Stem Cell-Derived Spinal Cord Astrocytes with Defined Mature or Reactive Phenotypes

Differentiation of astrocytes from human stem cells has significant potential for analysis of their role in normal brain function and disease, but existing protocols generate only immature astrocytes. Using early neuralization, we generated spinal cord astrocytes from mouse or human embryonic or in...

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Bibliographic Details
Main Authors: Laurent Roybon, Nuno J. Lamas, Alejandro Garcia-Diaz, Eun Ju Yang, Rita Sattler, Vernice Jackson-Lewis, Yoon A. Kim, C. Alan Kachel, Jeffrey D. Rothstein, Serge Przedborski, Hynek Wichterle, Christopher E. Henderson
Format: Article
Language:English
Published: Elsevier 2013-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713003136