Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils.

Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils.

Parasitic nematodes produce an unusual class of fatty acid and retinol (FAR)-binding proteins that may scavenge host fatty acids and retinoids. Two FARs from Brugia malayi (Bm-FAR-1 and Bm-FAR-2) were expressed as recombinant proteins, and their ligand binding, structural characteristics, and immuno...

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Bibliographic Details
Main Authors: Bin Zhan, Sridhar Arumugam, Malcolm W Kennedy, Nancy Tricoche, Lu-Yun Lian, Oluwatoyin A Asojo, Sasisekhar Bennuru, Maria Elena Bottazzi, Peter J Hotez, Sara Lustigman, Thomas R Klei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6193737?pdf=render

Internet

http://europepmc.org/articles/PMC6193737?pdf=render

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