The Effect of Astragaloside on Pacemaker Current and the Cytoskeleton in Rabbit Sinoatrial Node Cells Under the Ischemia and Reperfusion Condition

Objective: We investigated the role of astragaloside in the treatment of sick sinus syndrome (SSS).Methods: Neonatal New Zealand rabbits were selected for the study. Rabbit sinoatrial node (SAN) cells were isolated by the method of dual enzymatic digestion and differential adherence. The injury mode...

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Bibliographic Details
Main Authors: Ruxiu Liu, Jie Li, Yu Liu, Jie Peng, Xuanke Guan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00551/full