Transcriptional Landscape of PARs in Epithelial Malignancies

G protein-coupled receptors (GPCRs), the largest family of cell receptors, act as important regulators of diverse signaling pathways. Our understanding of the impact of GPCRs in tumors is emerging, yet there is no therapeutic platform based on GPCR driver genes. As cancer progresses, it disrupts nor...

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Bibliographic Details
Main Authors: Jeetendra Kumar Nag, Rachel Bar-Shavit
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
p53
ERE
ARE
Sp1
Online Access:https://www.mdpi.com/1422-0067/19/11/3451