Neonatal Alcohol Exposure in Mice Induces Select Differentiation- and Apoptosis-Related Chromatin Changes Both Independent of and Dependent on Sex

Neonatal Alcohol Exposure in Mice Induces Select Differentiation- and Apoptosis-Related Chromatin Changes Both Independent of and Dependent on Sex

Prenatal alcohol exposure (PAE) affects many aspects of physiology and behavior, including brain development. Specifically, ethanol can influence expression of genes important for brain growth, including chromatin modifiers. Ethanol can also increase apoptotic cell death in the brain and alter epige...

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Bibliographic Details
Main Authors: Samantha L. Schaffner, Alexandre A. Lussier, Jessica A. Baker, Dan Goldowitz, Kristin M. Hamre, Michael S. Kobor
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Genetics
Subjects:
neonatal alcohol exposure
epigenetics
chromatin
apoptosis
sex differences
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00035/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00035/full

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