Antibody Responses to Antigenic Targets of Recent Exposure Are Associated With Low-Density Parasitemia in Controlled Human Plasmodium falciparum Infections

Antibody Responses to Antigenic Targets of Recent Exposure Are Associated With Low-Density Parasitemia in Controlled Human Plasmodium falciparum Infections

The majority of malaria infections in low transmission settings remain undetectable by conventional diagnostics. A powerful model to identify antibody responses that allow accurate detection of recent exposure to low-density infections is controlled human malaria infection (CHMI) studies in which he...

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Bibliographic Details
Main Authors: Lotus L. van den Hoogen, Jona Walk, Tate Oulton, Isaie J. Reuling, Linda Reiling, James G. Beeson, Ross L. Coppel, Susheel K. Singh, Simon J. Draper, Teun Bousema, Chris Drakeley, Robert Sauerwein, Kevin K. A. Tetteh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
malaria
antibodies
exposure
controlled human malaria infection (CHMI)
sero-surveillance
sero-epidemiology
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03300/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03300/full

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