Aberrant NF-kappaB expression in autism spectrum condition: a mechanism for neuroinflammation

Aberrant NF-kappaB expression in autism spectrum condition: a mechanism for neuroinflammation

Autism Spectrum Condition (ASC) is recognised as having an inflammatory component. Post mortem brain samples from patients with ASC display neuroglial activation and inflammatory markers in cerebro-spinal fluid, although little is known about the underlying molecular mechanisms. Nuclear factor kappa...

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Bibliographic Details
Main Authors: Adam eYoung, Elaine eCampbell, Sarah eLynch, John eSuckling, Simon ePowis
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-05-01
Series:Frontiers in Psychiatry
Subjects:
Brain
Inflammation
pH
orbitofrontal cortex
NF-kB
autism spectrum condition
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2011.00027/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2011.00027/full

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