YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer

YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer

Histone modification recognition is an important mechanism for gene expression regulation in cancer. Here, the authors identify YEATS2 as a histone H3K27ac reader, regulating a transcriptional program essential for tumorigenesis in human non-small cell lung cancer.

Bibliographic Details
Main Authors: Wenyi Mi, Haipeng Guan, Jie Lyu, Dan Zhao, Yuanxin Xi, Shiming Jiang, Forest H. Andrews, Xiaolu Wang, Mihai Gagea, Hong Wen, Laszlo Tora, Sharon Y. R. Dent, Tatiana G. Kutateladze, Wei Li, Haitao Li, Xiaobing Shi
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01173-4

Internet

https://doi.org/10.1038/s41467-017-01173-4

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