New low-dose liquid pilocarpine formulation for treating dry mouth in Sjögren’s syndrome: clinical efficacy, symptom relief, and improvement in quality of life

New low-dose liquid pilocarpine formulation for treating dry mouth in Sjögren’s syndrome: clinical efficacy, symptom relief, and improvement in quality of life

Abstract Background Patients with Sjögren’s syndrome (SS) typically present clinically with xerostomia (dry mouth) because of progressive damage to the exocrine glands. We developed a new, low-dose pilocarpine/sodium alginate (LPA) solution with pilocarpine hydrochloride to inhibit systemic adverse...

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Bibliographic Details
Main Authors: Machiko Watanabe, Chisato Yamada, Yoshinori Komagata, Hirotoshi Kikuchi, Hiroyuki Hosono, Fumio Itagaki
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Sjögren’s syndrome
Pilocarpine
Xerostomia
Dry mouth
Sodium alginate
Online Access:http://link.springer.com/article/10.1186/s40780-018-0099-x

Internet

http://link.springer.com/article/10.1186/s40780-018-0099-x

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