Angiomyolipoma rebound tumor growth after discontinuation of everolimus in patients with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis.

INTRODUCTION:The EXIST-2 (NCT00790400) study demonstrated the superiority of everolimus over placebo for the treatment of renal angiomyolipomas associated with tuberous sclerosis complex (TSC) or sporadic lymphangioleiomyomatosis (LAM). This post hoc analysis of EXIST-2 study aimed to assess angiomy...

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Main Authors: John J Bissler, Norio Nonomura, Klemens Budde, Bernard A Zonnenberg, Michael Fischereder, Maurizio Voi, Anne-Laure Louveau, Fabian Herbst, E Martina Bebin, Paolo Curatolo, Andrea Zonta, Elena Belousova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6128468?pdf=render