Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer

Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer

Our previous studies have demonstrated that XIAP promotes bladder cancer metastasis through upregulating RhoGDIβ/MMP-2 pathway. However, the molecular mechanisms leading to the XIAP upregulation was unclear. In current studies, we found that XIAP was overexpressed in human high grade BCs, high metas...

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Bibliographic Details
Main Authors: Honglei Jin, Lei Xue, Lan Mo, Dongyun Zhang, Xirui Guo, Jiheng Xu, Jingxia Li, Minggang Peng, Xuewei Zhao, Minghao Zhong, Dazhong Xu, Xue-Ru Wu, Haishan Huang, Chuanshu Huang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Cell Adhesion & Migration
Subjects:
xiap
mir-200c
bladder cancer
invasion/metastasis
creb inactivation
Online Access:http://dx.doi.org/10.1080/19336918.2019.1633851

Internet

http://dx.doi.org/10.1080/19336918.2019.1633851

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