Genetic and pharmacological factors that influence reproductive aging in nematodes.

Age-related degenerative changes in the reproductive system are an important aspect of aging, because reproductive success is the major determinant of evolutionary fitness. Caenorhabditis elegans is a prominent organism for studies of somatic aging, since many factors that extend adult lifespan have...

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Bibliographic Details
Main Authors: Stacie E Hughes, Kimberley Evason, Chengjie Xiong, Kerry Kornfeld
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1797816?pdf=render