Platelet Activation Is Triggered by Factors Secreted by Senescent Endothelial HMEC-1 Cells In Vitro

Platelet Activation Is Triggered by Factors Secreted by Senescent Endothelial HMEC-1 Cells In Vitro

Aging is one of the main risk factors for the development of chronic diseases, with both the vascular endothelium and platelets becoming functionally altered. Cellular senescence is a form of permanent cell cycle arrest initially described in primary cells propagated in vitro, although it can also b...

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Bibliographic Details
Main Authors: Whitney Venturini, Alexandra Olate-Briones, Claudio Valenzuela, Diego Méndez, Eduardo Fuentes, Angel Cayo, Daniel Mancilla, Raul Segovia, Nelson E. Brown, Rodrigo Moore-Carrasco
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
platelets
cellular senescence
doxorubicin
endothelial cells
SASP
Online Access:https://www.mdpi.com/1422-0067/21/9/3287

Internet

https://www.mdpi.com/1422-0067/21/9/3287

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