Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen.

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen.

Throughout the last several decades, vaccination has been key to prevent and eradicate infectious diseases. However, many pathogens (e.g., respiratory syncytial virus [RSV], influenza, dengue, and others) have resisted vaccine development efforts, largely because of the failure to induce potent anti...

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Bibliographic Details
Main Authors: Fabian Sesterhenn, Marie Galloux, Sabrina S Vollers, Lucia Csepregi, Che Yang, Delphyne Descamps, Jaume Bonet, Simon Friedensohn, Pablo Gainza, Patricia Corthésy, Man Chen, Stéphane Rosset, Marie-Anne Rameix-Welti, Jean-François Éléouët, Sai T Reddy, Barney S Graham, Sabine Riffault, Bruno E Correia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000164

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https://doi.org/10.1371/journal.pbio.3000164

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