Beyond the binding site: the role of the β₂-β₃ loop and extra-domain structures in PDZ domains.

A general paradigm to understand protein function is to look at properties of isolated well conserved domains, such as SH3 or PDZ domains. While common features of domain families are well understood, the role of subtle differences among members of these families is less clear. Here, molecular dynam...

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Bibliographic Details
Main Authors: Stefano Mostarda, David Gfeller, Francesco Rao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22412368/pdf/?tool=EBI