The Endothelium in Acromegaly

Growth hormone (GH) and insulin like growth factor-1 (IGF-1) excess induce well-known deleterious effects on the cardiovascular system, especially after long-term exposition. Acromegaly, a condition of chronic GH and IGF-1 hypersecretion, is frequently associated to cardiovascular complications, alt...

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Bibliographic Details
Main Authors: Pietro Maffei, Francesca Dassie, Alexandra Wennberg, Matteo Parolin, Roberto Vettor
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Endocrinology
Subjects:
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Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00437/full