Effect of Tumour Necrosis Factor-Alpha on Estrogen Metabolic Pathways in Breast Cancer Cells

<p>Tumor necrosis factor-alpha (TNF-&#945;) is a proinflammatory cytokine that has been linked to breast cancer development. Estrogen metabolic pathway is also involved in breast carcinogenesis and DNA adducts formation. In this study we investigated the effect of TNF-&#945; on the est...

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Bibliographic Details
Main Author: Marwa Kamel, Samia Shouman, Mahmoud El-Merzebany, Gokhan Kilic, Timothy Veenstra, Muhammad Saeed, Mohamed Wagih, Concepcion Diaz-Arrastia, Deepa Patel, Salama Salama
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:Journal of Cancer
Online Access:http://www.jcancer.org/v03p0310.htm