Ameliorative effect of gallic acid on methotrexate-induced hepatotoxicity and nephrotoxicity in rat

We investigated the protective effect of gallic acid (GA) against methotrexate (MTX)-induced hepatotoxicity and nephrotoxicity. Male Wistar rats were randomized into five groups (n = 6/group): I, control; II, MTX-treated for seven days; III, pre-treated with GA for seven days, followed by MTX for se...

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Bibliographic Details
Main Authors: Ebenezer Tunde Olayinka, Ayokanmi Ore, Oluwatobi Adewumi Adeyemo, Olaniyi Solomon Ola
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Journal of Xenobiotics
Subjects:
Online Access:http://www.pagepressjournals.org/index.php/xeno/article/view/6092