Role of Epstein-Barr Virus in Pathogenesis and Racial Distribution of IgA Nephropathy

Role of Epstein-Barr Virus in Pathogenesis and Racial Distribution of IgA Nephropathy

IgA nephropathy (IgAN) is the dominant type of primary glomerulonephritis worldwide. However, IgAN rarely affects African Blacks and is uncommon in African Americans. Polymeric IgA1 with galactose-deficient hinge-region glycans is recognized as auto-antigen by glycan-specific antibodies, leading to...

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Bibliographic Details
Main Authors: Katerina Zachova, Petr Kosztyu, Josef Zadrazil, Karel Matousovic, Karel Vondrak, Petr Hubacek, Bruce A. Julian, Zina Moldoveanu, Zdenek Novak, Klara Kostovcikova, Milan Raska, Jiri Mestecky
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
IgA
EBV-Epstein-Barr virus
racial distribution
IgA nephropathy
mucosal immunology
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00267/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00267/full

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