How much remains undetected? Probability of molecular detection of human Plasmodia in the field.

In malaria endemic areas, most people are simultaneously infected with different parasite clones. Detection of individual clones is hampered when their densities fluctuate around the detection limit and, in case of P. falciparum, by sequestration during part of their life cycle. This has important i...

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Bibliographic Details
Main Authors: Cristian Koepfli, Sonja Schoepflin, Michael Bretscher, Enmoore Lin, Benson Kiniboro, Peter A Zimmerman, Peter Siba, Thomas A Smith, Ivo Mueller, Ingrid Felger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084249?pdf=render