In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide

Although the physicochemical properties of antimicrobial peptides (AMPs) and anticancer peptides (ACPs) are very similar, it remains unclear which specific parameter(s) of ACPs confer the major anticancer activity. By answering how to construct a short AMP/ACP that could easily be synthesized in the...

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Bibliographic Details
Main Authors: Rui Ma, Sin Wa Wong, Lilin Ge, Chris Shaw, Shirley W.I. Siu, Hang Fai Kwok
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770519301020