Human osteochondritis dissecans fragment-derived chondrocyte characteristics ex vivo, after monolayer expansion-induced de-differentiation, and after re-differentiation in alginate bead culture

Human osteochondritis dissecans fragment-derived chondrocyte characteristics ex vivo, after monolayer expansion-induced de-differentiation, and after re-differentiation in alginate bead culture

Abstract Background Autologous chondrocyte implantation (ACI) is a therapy for articular cartilage and osteochondral lesions that relies on notch- or trochlea-derived primary chondrocytes. An alternative cell source for ACI could be osteochondritis dissecans (OCD) fragment-derived chondrocytes. Asse...

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Bibliographic Details
Main Authors: Matthias Aurich, Gunther O. Hofmann, Florian Gras, Bernd Rolauffs
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Chondrocyte
Articular cartilage
De-differentiation
Re-differentiation
Monolayer expansion
Alginate bead culture
Online Access:http://link.springer.com/article/10.1186/s12891-018-2079-6

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http://link.springer.com/article/10.1186/s12891-018-2079-6

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