On chaotic dynamics in transcription factors and the associated effects in differential gene regulation

It is becoming clear that the dynamics of transcription factors may be important for gene regulation. Here, the authors study the implications of oscillatory and chaotic dynamics of NF-κB and demonstrate that it allows a degree of control of gene expression and can generate phenotypic heterogeneity....

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Bibliographic Details
Main Authors: Mathias L. Heltberg, Sandeep Krishna, Mogens H. Jensen
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07932-1