Solid Lipid Nanoparticles Loaded with Glucocorticoids Protect Auditory Cells from Cisplatin-Induced Ototoxicity

Solid Lipid Nanoparticles Loaded with Glucocorticoids Protect Auditory Cells from Cisplatin-Induced Ototoxicity

Cisplatin is a chemotherapeutic agent that causes the irreversible death of auditory sensory cells, leading to hearing loss. Local administration of cytoprotective drugs is a potentially better option co-therapy for cisplatin, but there are strong limitations due to the difficulty of accessing the i...

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Bibliographic Details
Main Authors: Blanca Cervantes, Lide Arana, Silvia Murillo-Cuesta, Marina Bruno, Itziar Alkorta, Isabel Varela-Nieto
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Journal of Clinical Medicine
Subjects:
nanocarriers
dexamethasone
hydrocortisone
otic protection
stearic acid-based solid lipid nanoparticle (SLN)
Online Access:https://www.mdpi.com/2077-0383/8/9/1464

Internet

https://www.mdpi.com/2077-0383/8/9/1464

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