Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer

Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer

Previous studies reported that Follistatin-like 3 (FSTL3) is abundantly expressed in several solid tumors and participate in the regulation of cell metabolism. However, the clinico-pathological significance, biological role and molecular mechanism of FSTL3 in colorectal cancer (CRC) is still unclear...

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Bibliographic Details
Main Authors: Yuqiang Li, Mengxiang Tian, Wenxue Liu, Dan Wang, Zhongyi Zhou, Qian Pei, Yan Huang, Fengbo Tan, Cenap Güngör
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
FSTL3
β-Catenin
colorectal cancer
EMT
aerobic glycolysis
metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.660159/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.660159/full

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