Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes

Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes

Ex vivo transduction of human CD34+ hematopoietic stem/progenitor cells (hCD34+ HSPCs) and T lymphocytes is a key process that requires high efficiency and low toxicity to achieve effective clinical results. So far, several enhancers have been used to improve this process. Among them, Retronectin hi...

Full description

Bibliographic Details
Main Authors: Claudia Piovan, Virna Marin, Cinzia Scavullo, Stefano Corna, Erica Giuliani, Sergio Bossi, Anne Galy, David Fenard, Claudio Bordignon, Gian Paolo Rizzardi, Chiara Bovolenta
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
lentiviral vector
transduction
HSC
T lymphocytes
additive
peptide
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050117300438

Similar Items

Similar Items