Genetic Ablation and Guanylyl Cyclase/Natriuretic Peptide Receptor-A: Impact on the Pathophysiology of Cardiovascular Dysfunction

Genetic Ablation and Guanylyl Cyclase/Natriuretic Peptide Receptor-A: Impact on the Pathophysiology of Cardiovascular Dysfunction

Mice bearing targeted gene mutations that affect the functions of natriuretic peptides (NPs) and natriuretic peptide receptors (NPRs) have contributed important information on the pathogenesis of hypertension, kidney disease, and cardiovascular dysfunction. Studies of mice having both complete gene...

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Bibliographic Details
Main Author: Kailash N. Pandey
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
atrial natriuretic peptide
guanylyl cyclase/natriuretic peptide receptor-A
gene-knockout
gene-duplication
hypertension
congestive heart failure
Online Access:https://www.mdpi.com/1422-0067/20/16/3946

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https://www.mdpi.com/1422-0067/20/16/3946

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