Single-cell transcriptome analysis of CD8+ T-cell memory inflation [version 1; peer review: 2 approved]
Background: Persistent viruses such as murine cytomegalovirus (MCMV) and adenovirus-based vaccines induce strong, sustained CD8+ T-cell responses, described as memory “inflation”. These retain functionality, home to peripheral organs and are associated with a distinct transcriptional program. Method...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wellcome
2019-05-01
|
Series: | Wellcome Open Research |
Online Access: | https://wellcomeopenresearch.org/articles/4-78/v1 |