Single-cell transcriptome analysis of CD8+ T-cell memory inflation [version 1; peer review: 2 approved]
Background: Persistent viruses such as murine cytomegalovirus (MCMV) and adenovirus-based vaccines induce strong, sustained CD8+ T-cell responses, described as memory “inflation”. These retain functionality, home to peripheral organs and are associated with a distinct transcriptional program. Method...
Main Authors: | Andrew J. Highton, Madeleine E. Zinser, Lian Ni Lee, Claire L. Hutchings, Catherine De Lara, Chansavath Phetsouphanh, Chris B. Willberg, Claire L. Gordon, Paul Klenerman, Emanuele Marchi |
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Format: | Article |
Language: | English |
Published: |
Wellcome
2019-05-01
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Series: | Wellcome Open Research |
Online Access: | https://wellcomeopenresearch.org/articles/4-78/v1 |
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