New Conjugated Compound T5 Epidioxy-Sterol-ANB Inhibits the Growth of Mycobacterium tuberculosis Affecting the Cholesterol and Folate Pathways

New Conjugated Compound T5 Epidioxy-Sterol-ANB Inhibits the Growth of Mycobacterium tuberculosis Affecting the Cholesterol and Folate Pathways

The upsurge and persistence of drug resistant strains of Mycobacterium tuberculosis (Mtb) is an important limitant to the battery of drugs available for the elimination of tuberculosis (TB). To avoid future scarcity of antibiotics against Mtb, it is important to discover new effective anti-mycobacte...

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Bibliographic Details
Main Authors: Andres Baena, Emanuel Vasco, Manuel Pastrana, Juan F. Alzate, Luis F. Barrera, Alejandro Martínez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Microbiology
Subjects:
antimicobacterial
macrophages
cholesterol pathway
folic acid pathway
Mycobacterium tuberculosis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.537935/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.537935/full

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