Context-Dependent Impact of RAS Oncogene Expression on Cellular Reprogramming to Pluripotency

Summary: Induction of pluripotency in somatic cells with defined genetic factors has been successfully used to investigate the mechanisms of disease initiation and progression. Cellular reprogramming and oncogenic transformation share common features; both involve undergoing a dramatic change in cel...

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Bibliographic Details
Main Authors: Alba Ferreirós, Pablo Pedrosa, Sabela Da Silva-Álvarez, Francisco Triana-Martínez, Jéssica M. Vilas, Pilar Picallos-Rabina, Patricia González, María Gómez, Han Li, Tomás García-Caballero, Miguel González-Barcia, Anxo Vidal, Manuel Collado
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119301286