Pathogenic role of glycan-specific IgG antibodies in IgA nephropathy

Pathogenic role of glycan-specific IgG antibodies in IgA nephropathy

Abstract Background Accumulating evidences proved the important roles of circulating IgA1-containing immune complexes (cIgA1) in IgA nephropathy (IgAN). Galactose-deficient IgA1 (Gd-IgA1) and glycan-specific IgG antibody have been identified as major components in cIgA1. Before, Gd-IgA1 was reported...

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Bibliographic Details
Main Authors: Yan-feng Zhao, Li Zhu, Li-jun Liu, Su-fang Shi, Ji-cheng Lv, Hong Zhang
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Nephrology
Subjects:
IgA nephropathy
Glycan-specific IgG antibody
Galactose-deficient IgA1
Online Access:http://link.springer.com/article/10.1186/s12882-017-0722-3

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http://link.springer.com/article/10.1186/s12882-017-0722-3

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