MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates.

MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates.

While multiple studies have reported the accelerated evolution of brain gene expression in the human lineage, the mechanisms underlying such changes are unknown. Here, we address this issue from a developmental perspective, by analyzing mRNA and microRNA (miRNA) expression in two brain regions withi...

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Bibliographic Details
Main Authors: Mehmet Somel, Xiling Liu, Lin Tang, Zheng Yan, Haiyang Hu, Song Guo, Xi Jiang, Xiaoyu Zhang, Guohua Xu, Gangcai Xie, Na Li, Yuhui Hu, Wei Chen, Svante Pääbo, Philipp Khaitovich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22162950/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22162950/pdf/?tool=EBI

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