MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells

MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells

Abstract Background Cellular aging may be associated with epigenetics. Methyl-CpG-binding protein 2 (MeCP2) and sirtuin 1 (SIRT1) are two important epigenetic factors. Our former work demonstrated that MeCP2 expression increased and SIRT1 expression decreased in senescent endothelial progenitor cell...

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Bibliographic Details
Main Authors: Chunli Wang, Fei Wang, Zhen Li, Qing Cao, Liya Huang, Shuyan Chen
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Stem Cell Research & Therapy
Subjects:
Endothelial progenitor cells
Senescence
MeCP2
SIRT1
Epigenetic
Online Access:http://link.springer.com/article/10.1186/s13287-018-0828-y

Internet

http://link.springer.com/article/10.1186/s13287-018-0828-y

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