Refractory Hypothyroidism Due to Improper Storage of Levothyroxine Tablets

ContextA not negligible part of hypothyroid patients on levothyroxine therapy do not normalize serum thyrotropin (TSH) concentrations. “Refractory hypothyroidism,” i.e., a condition characterized by persistently abnormal serum TSH levels despite adequate titration of l-T4 substitution therapy, requi...

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Bibliographic Details
Main Authors: Salvatore Benvenga, Giampaolo Papi, Alessandro Antonelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00155/full