Infection With Clostridioides difficile Attenuated Collagen-Induced Arthritis in Mice and Involved Mesenteric Treg and Th2 Polarization

Infection With Clostridioides difficile Attenuated Collagen-Induced Arthritis in Mice and Involved Mesenteric Treg and Th2 Polarization

ObjectivesRheumatoid arthritis is an autoimmune disease with multifactorial etiopathogenesis. Among the environmental factors, mucosal infections and the inducing pathobionts are gaining increasing attention. We here set out to explore the gut-joint-axis and the impact of Clostridioides difficile in...

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Bibliographic Details
Main Authors: Christian Johann Schmidt, Katharina Wenndorf, Meinolf Ebbers, Johann Volzke, Michael Müller, Julia Strübing, Katja Kriebel, Susanne Kneitz, Bernd Kreikemeyer, Brigitte Müller-Hilke
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
collagen-induced arthritis
Clostridioides difficile
microbiome
Treg-polarization
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.571049/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.571049/full

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