Neuroprotective Effects of Serpina3k in Traumatic Brain Injury

Neuroprotective Effects of Serpina3k in Traumatic Brain Injury

Traumatic brain injury (TBI) is a major cause of disability and mortality worldwide, in part resulting from secondary apoptosis of neurons in peri-contusion areas. Serpina3k, a serine protease inhibitor, has been shown to inhibit apoptosis in injury models. In this study, we investigated the anti-ap...

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Bibliographic Details
Main Authors: Yao Jing, Dianxu Yang, Yimu Fu, Wei Wang, Guoyuan Yang, Fang Yuan, Hao Chen, Jun Ding, Shiwen Chen, Hengli Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neurology
Subjects:
serpina3k
traumatic brain injury
mouse model
SH-SY5Y cells
apoptosis
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01215/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01215/full

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