Wiskott-Aldrich Syndrome Protein Regulates Leukocyte-Dependent Breast Cancer Metastasis

Wiskott-Aldrich Syndrome Protein Regulates Leukocyte-Dependent Breast Cancer Metastasis

A paracrine interaction between epidermal growth factor (EGF)-secreting tumor-associated macrophages (TAMs) and colony-stimulating factor 1 (CSF-1)-secreting breast carcinoma cells promotes invasion and metastasis. Here, we show that mice deficient in the hematopoietic-cell-specific Wiskott-Aldrich...

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Bibliographic Details
Main Authors: Dan Ishihara, Athanassios Dovas, Lorena Hernandez, Maria Pozzuto, Jeffrey Wyckoff, Jeffrey E. Segall, John S. Condeelis, Anne R. Bresnick, Dianne Cox
Format: Article
Language:English
Published: Elsevier 2013-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713003549

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http://www.sciencedirect.com/science/article/pii/S2211124713003549

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